Johns Hopkins University · NeuroscienceCalabresi Lab
Peter A Calabresi · Baltimore, Maryland
Research Focus
Dr. Peter A Calabresi’s research lab focuses on understanding how multiple sclerosis (MS) progresses and how we can predict its course in patients. By using advanced imaging techniques like MRI and optical coherence tomography, they study changes in the brain and retina that occur as MS advances. The goal is to develop better tools to monitor patients and guide treatment decisions, ultimately improving care for those with MS.
multiple sclerosisneurodegenerationMRIoptical coherence tomographybrain imagingretinal imagingCNSmetabolismaxon lossdemyelination
Research Aims
3AIM 01Determine if transsynaptic degeneration (TSD) predicts whole brain atrophy in MS.
AIM 02Assess microstructural features of lesions in relation to neurodegeneration and disability.
AIM 03Evaluate how metabolic indicators like oxygen extraction fraction (OEF) relate to neurodegeneration in MS.
Skills the Lab Values
MRI techniquesoptical coherence tomography (OCT)magnetic susceptibility mapping (QSM)multi-shell diffusion MRIquantitative T1 lesion mapping (QT1M)data analysis using imaging softwareclinical trial designretinal angiographystatistical analysisbiological sample processing
Output against the department
Publications908top 4% of dept.30th of 671
this lab
most publishedleast published
Citations61ktop 5% of dept.33rd of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.