New York University · BiologyMetastasis Research Hub
Eva Hernando · New York, New York
Research Focus
Dr. Eva Hernando's lab at NYU School of Medicine focuses on understanding the mechanisms behind cancer metastasis, particularly in melanoma and brain tumors. The lab investigates how certain proteins and epigenetic changes affect tumor spread and explores new therapeutic strategies to inhibit brain metastasis. Ultimately, the research aims to improve treatment options for patients with limited prospects.
brain metastasismelanomaepigeneticstumor heterogeneitytherapeutic strategies
Research Aims
5AIM 01Develop new therapies targeting amyloid-beta to reduce brain metastasis in melanoma.
AIM 02Investigate the role of NR2F2-isoform 2 in melanoma cell de-differentiation and metastasis.
AIM 03Characterize the effects of epigenetic changes on melanoma tumor heterogeneity.
AIM 04Assess the therapeutic potential of antibodies and small molecules in preclinical models.
AIM 05Understand the microenvironmental influences on brain metastasis.
Skills the Lab Values
cell culturexenograft modelsproteomicsRNA sequencinggenetic manipulation
Output against the department
Publications317top 17% of dept.176th of 1,033
this lab
most publishedleast published
Citations20ktop 20% of dept.208th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.