WMCWeill Medical College of Cornell University · Neuroscience
The Neural Genesis Lab
Margaret Elizabeth Ross · New York, New York
Research Focus
Dr. Margaret Elizabeth Ross's lab at Weill Medical College focuses on understanding the genetic factors that contribute to spina bifida, a serious neural tube defect. By combining advanced DNA sequencing and machine learning techniques, the lab aims to identify specific gene mutations and interactions that lead to the condition. Their research strives not only to uncover the biological mechanisms behind spina bifida but also to pave the way for better prevention strategies and treatment options for affected individuals.
spina bifidagenetic predispositionneural tube defectsmachine learninggenomicsCRISPRstem cellsRNA sequencinggene expression
Research Aims
3AIM 01Identify gene variants associated with spina bifida using comprehensive genomic analysis.
AIM 02Test the functional significance of identified gene variants in stem cell models.
AIM 03Examine gene interaction effects on spina bifida using CRISPR-edited mouse models.
Skills the Lab Values
CRISPRRNA sequencingDNA sequencingcell culturemouse modelsgenome analysismachine learning3-D cell culture methodscomputational biology
Output against the department
Publications194top 38% of dept.256th of 671
this lab
most publishedleast published
Citations13ktop 31% of dept.207th of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.