Georgia Institute of Technology-Main Campus · EngineeringCancer Detection and T Cell Engineering Lab
Gabriel A Kwong · Atlanta, Georgia
Research Focus
Dr. Gabriel A. Kwong's lab at Georgia Institute of Technology focuses on innovative approaches to cancer detection and therapy using engineered T cells. The lab is developing advanced biosensing technologies that can identify dormant cancer cells, particularly in cases like estrogen receptor-positive breast cancer. By utilizing techniques such as DNA-gated sorting and T cell engineering, the lab aims to monitor the reawakening of cancer and improve therapeutic strategies for cell-based cancer treatments.
cancer detectionT cell engineeringbiosensorsdormant cancermultiplexed sortingCD8 T cellsDNA-gated cytometryantibody engineeringcell therapy
Research Aims
5AIM 01Develop engineered T cell biosensors to detect dormant cancer cells.
AIM 02Create technologies for multiplexed sorting of antigen-specific CD8 T cells.
AIM 03Investigate the expression of proteases as indicators of dormant cancer reawakening.
AIM 04Establish protocols for isolating and analyzing rare T cell populations.
AIM 05Explore the use of synthetic biomarkers in cancer detection.
Skills the Lab Values
T cell cultureDNA sequencingflow cytometryimmunoassayscell sortingprotein engineeringgenetic circuit designanimal modelsbiomarker analysis
Output against the department
Publications82bottom 16% of dept.233rd of 278
this lab
most publishedleast published
Citations4.3kbottom 33% of dept.186th of 278
this lab
most citedleast cited
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