UWMUniversity of Wisconsin-Madison · Biology
Cardiac Regeneration Lab
Junsu Kang · Madison, Wisconsin
Research Focus
Dr. Junsu Kang's lab at the University of Wisconsin-Madison focuses on understanding how zebrafish can repair their hearts after injury. By studying the genetic and cellular mechanisms involved in this regeneration process, the lab aims to uncover potential strategies for healing hearts in humans, particularly after damage from disease or trauma. This innovative research could lead to groundbreaking treatments for heart diseases, which remain a leading cause of death worldwide.
heart regenerationzebrafishgene regulatory networksepigeneticstranscription factorscell proliferationcardiac repairnatural regenerationenhancer analysis
Research Aims
3AIM 01Investigate the transcription factors involved in il11a-triggered heart regeneration.
AIM 02Define the cluster of cardiac regeneration enhancers that control gene expression during heart repair.
AIM 03Differentiate between the genetic responses to heart injury and those to heart regeneration.
Skills the Lab Values
PCRzebrafish breeding and genetic manipulationepigenomic analysistransgenic assaysbiochemical assaysRNA sequencingcomputational analysisCUT&Tagcell culture
Output against the department
Publications51bottom 12% of dept.904th of 1,033
this lab
most publishedleast published
Citations924bottom 4% of dept.991st of 1,033
this lab
most citedleast cited
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