New York University · Biomedical EngineeringLionnet Lab
Timothee Lionnet · New York, New York
Research Focus
Dr. Timothee Lionnet's research lab at NYU focuses on understanding the molecular mechanisms of aging and transcription regulation. The lab uses synthetic biology and advanced imaging techniques to explore how specific proteins are involved in the aging process and how they regulate gene expression. By manipulating these proteins, the lab aims to develop innovative strategies to combat aging-related diseases and improve gene regulation technologies.
agingtranscription factorssynthetic biologygene regulationprotein dynamicslive imagingZinc Finger technologycell signalingpost-translational modifications
Research Aims
5AIM 01Dissect CEBPB isoform functions and their role in aging.
AIM 02Develop synthetic tools to visualize CEBPB dynamics in individual cells.
AIM 03Explore binding kinetics of transcription factors in live cells.
AIM 04Investigate how transcription factors find their target sequences in the genome.
AIM 05Establish designer proteins to manipulate genetic transcription.
Skills the Lab Values
synthetic biologysingle-molecule tracking microscopyDNA manipulationcell culturefluorescence imagingbinding kinetics measurementprotein analysislive cell imagingmolecular cloning
Output against the department
Publications110bottom 21% of dept.472nd of 595
this lab
most publishedleast published
Citations8.3ktop 41% of dept.244th of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.