Harvard University · GeneticsPerrimon Lab
Norbert Perrimon · Cambridge, Massachusetts
Research Focus
Dr. Norbert Perrimon's lab at Harvard Medical School focuses on understanding critical biological processes through the study of Drosophila, a model organism. The ongoing research explores immune signaling in ticks to improve our knowledge of tick-borne diseases, molecular mechanisms of muscle growth and wasting to address health issues like sarcopenia, and the communication between different organs as they age. By leveraging advanced technologies, the lab aims to uncover fundamental biological pathways relevant to human health.
tick immune signalingDrosophilamuscle autophagyaginginter-organ communication
Research Aims
5AIM 01Characterize immune signaling pathways in ticks to understand responses to infection.
AIM 02Investigate the role of autophagy in muscle growth and wasting in Drosophila.
AIM 03Explore interorgan communication related to aging mechanisms in Drosophila.
AIM 04Identify novel molecular components involved in the regulation of immune signaling.
AIM 05Utilize multi-omics to uncover metabolic changes associated with aging.
Skills the Lab Values
PCRcell cultureRNA sequencingsingle-cell transcriptomicsproteomicsmetabolomicsbioinformaticsWestern blotmicroscopyCRISPR
Output against the department
Publications866top 5% of dept.14th of 259
this lab
most publishedleast published
Citations94ktop 5% of dept.14th of 259
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.