University of Washington-Seattle Campus · EngineeringAverkiou Lab
Michalakis Averkiou · Seattle, Washington
Research Focus
Dr. Michalakis Averkiou's lab at the University of Washington focuses on improving treatments for liver cancer by using an innovative combination of ultrasound techniques and mechanotherapeutic drugs. Their goal is to enhance the delivery of chemotherapy to tumors, helping to overcome challenges posed by the tumor microenvironment. This research aims to make cancer treatments more effective and ultimately improve patient outcomes.
Hepatocellular carcinomaultrasound cavitationmechanotherapeuticstumor microenvironmentchemotherapydrug deliveryprecision medicinecancer treatment
Research Aims
4AIM 01Evaluate how mechanotherapeutic drugs can modify the tumor microenvironment to improve drug delivery.
AIM 02Assess the effectiveness of ultrasound cavitation in enhancing drug delivery for liver cancer treatment.
AIM 03Investigate the combined effects of mechanotherapeutics and ultrasound cavitation on tumor microenvironments.
AIM 04Test the preclinical effectiveness of combined therapies on tumor survival outcomes.
Skills the Lab Values
ultrasound imagingmechanotransduction techniquesin vivo animal modelsimmunohistochemistrydrug delivery system designbiophysical modelingdata analysis softwareclinical trial designmicrobubble technology
Output against the department
Publications143bottom 34% of dept.183rd of 278
this lab
most publishedleast published
Citations3.7kbottom 28% of dept.200th of 278
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.