RURush University · Physiology
Cardiac Dynamics and Arrhythmia Lab
Kathrin Banach · Chicago, Illinois
Research Focus
Dr. Kathrin Banach's lab investigates the mechanisms of cardiac alternans and their relationship to atrial fibrillation, a serious cardiac condition. The research focuses on how calcium signaling affects the electrical and mechanical functions of heart cells, particularly in the atria. By studying these connections at the cellular and organ levels, the lab aims to identify factors that contribute to arrhythmias and explore potential therapies.
calcium signalingatrial fibrillationcardiac alternanscell communicationarrhythmia
Research Aims
3AIM 01Establish a mechanistic model of atrial excitation-contraction coupling and alternans.
AIM 02Investigate FDUF-dependent mechanisms in atrial alternans.
AIM 03Determine the spatio-temporal organization of calcium and voltage-driven alternans.
Skills the Lab Values
calcium imagingelectrophysiologyin vivo imagingmouse modelscell culturepharmacological testingdata modelingtissue perfusionWestern blot
Output against the department
Publications75bottom 16% of dept.240th of 286
this lab
most publishedleast published
Citations1.7kbottom 9% of dept.261st of 286
this lab
most citedleast cited
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