University of Pennsylvania · NeuroscienceLitt Lab
Brian Litt · Philadelphia, Pennsylvania
Research Focus
The research lab led by Brian Litt at the University of Pennsylvania focuses on improving surgery outcomes for patients with epilepsy who do not respond to medication. By developing advanced methods to analyze brain imaging and electrical activity, the lab aims to create personalized approaches that help identify the best surgical options for individual patients. The lab collaborates with multiple surgical centers to standardize data sharing and improve surgical strategies for epilepsy treatment.
epilepsysurgeryneuroimagingnetwork modelsStereo EEGclinical outcomesdata standardization
Research Aims
4AIM 01Develop methods to map epileptic networks from imaging and Stereo EEG data.
AIM 02Create tools to select optimal surgical interventions for epilepsy patients.
AIM 03Establish protocols for assessing sampling bias in SEEG studies.
AIM 04Collaborate with multiple centers to standardize and validate surgical techniques.
Skills the Lab Values
Stereo EEG analysisbrain imaging techniquesdata modelingelectroencephalography (EEG)clinical trial designmachine learning algorithmsbioengineering techniquesinterventional neurology
Output against the department
Publications319top 21% of dept.141st of 671
this lab
most publishedleast published
Citations22ktop 19% of dept.126th of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.