Yale University · GeneticsSozen Lab
Berna Sozen · New Haven, Connecticut
Research Focus
Dr. Berna Sozen's lab at Yale University focuses on understanding early human embryonic development using advanced stem cell technology. By creating models of the human epiblast, her research aims to explore how cells differentiate into various types during embryogenesis and how factors like metabolism influence these processes. Ultimately, the lab's work seeks to provide insights into developmental disorders and contribute to more effective stem cell therapies.
embryonic developmenthuman pluripotent stem cellscell differentiationdisease modeling3D cell culturedevelopmental geneticscellular metabolismcongenital disordersbioengineering
Research Aims
5AIM 01Utilize human pluripotent stem cells to model early embryonic development.
AIM 02Investigate the mechanisms of cell differentiation in human embryonic tissues.
AIM 03Analyze the influence of cellular metabolism on embryonic development.
AIM 04Understand the molecular events that lead to developmental disorders.
AIM 05Develop innovative bioengineering techniques for disease modeling.
Skills the Lab Values
human pluripotent stem cell culture3D cell culture techniquessingle-cell multi-omicsgenetic imaginghigh-throughput computational analysismetabolomicsbioengineeringexperimental designdata analysis
Output against the department
Publications57bottom 10% of dept.232nd of 259
this lab
most publishedleast published
Citations2.3kbottom 11% of dept.231st of 259
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.