UTHThe University of Texas Health Science Center at Houston · Microbiology & Immunology
Trypanosome Division and Drug Target Lab
Ziyin Li · Houston, Texas
Research Focus
Dr. Ziyin Li's lab at the University of Texas Health Science Center Houston focuses on understanding how a specific protozoan parasite, Trypanosoma brucei, divides and grows. This research is significant because it could lead to new treatments for human African Trypanosomiasis, a disease that currently has limited and toxic medications. By studying the unique process of cell division in this parasite, the lab aims to identify new drug targets that could help fight this serious disease.
Trypanosoma bruceicytokinesiscell divisiondrug targetskinesin proteinsparasitic diseasesmicrotubulesproteinssignal transductionpublic health
Research Aims
3AIM 01Determine the functional interplay among known cytokinesis regulatory proteins.
AIM 02Dissect the function of a kinesin-13 family protein in cytokinesis.
AIM 03Investigate the role of KLIF-associated cytoskeletal proteins in cleavage furrow ingression.
Skills the Lab Values
cell culturemolecular cloningbiochemical assaysprotein purificationmicroscopygenetic manipulationRNA interferenceWestern blotdata analysisbioinformatics
Output against the department
Publications190top 34% of dept.165th of 486
this lab
most publishedleast published
Citations4.9kbottom 36% of dept.309th of 486
this lab
most citedleast cited
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