Duke University · BiologyDi Talia Lab
Stefano Di Talia · Durham, North Carolina
Research Focus
Dr. Stefano Di Talia's lab at Duke University studies how cells and tissues develop and regenerate. They focus on understanding the signaling mechanisms that guide the formation of structures like the spine in zebrafish and how these processes relate to bone healing. Their research combines genetics, cell biology, and advanced imaging techniques to explore these biological phenomena, potentially leading to new insights into regeneration and tissue development in humans.
notochordbone regenerationzebrafishDrosophila embryogenesiscell cyclemorphogenesisimaging techniquessignal transduction
Research Aims
5AIM 01Investigate the signaling mechanisms behind notochord segmentation in zebrafish.
AIM 02Examine how osteoblasts contribute to bone regeneration during injury in zebrafish.
AIM 03Understand the integration of the cell cycle and cytoskeletal dynamics during embryonic development in Drosophila.
AIM 04Identify patterns in signaling pathways that drive skeletal regeneration in zebrafish.
AIM 05Dissect how cellular behaviors are coordinated to ensure proper morphogenesis during development.
Skills the Lab Values
Genetic manipulation in zebrafishLive cell imagingHistologyMicroscopy techniquesQuantitative data analysisCell cultureMolecular cloningTranscriptional profilingCRISPR
Output against the department
Publications95bottom 33% of dept.693rd of 1,033
this lab
most publishedleast published
Citations3.8kbottom 29% of dept.732nd of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.