University of California-San Francisco · PhysiologyDendrite Development and Regeneration Lab
Yuh Nung Jan · San Francisco, California
Research Focus
Dr. Yuh Nung Jan's lab at UCSF focuses on understanding how dendrites, the branches of neurons that receive signals, develop and regenerate. The lab uses fruit flies to uncover the genetic and molecular mechanisms that control these processes. This research is important since defects in dendrite development can be linked to neurological disorders like autism and Down syndrome. By studying how neurons communicate and respond to injury, the lab aims to contribute to potential treatments for these conditions.
dendrite developmentneuroregenerationmechano-sensationDrosophilaneurological disordersion channelscell surface proteomicsaxon regenerationgenetic mechanisms
Research Aims
3AIM 01Identify genes that control dendrite development in sensory neurons.
AIM 02Explore how mechano-sensitive ion channels function in neurons.
AIM 03Investigate the mechanisms underlying neuronal injury response and regeneration.
Skills the Lab Values
Drosophila geneticscell culturecryo-electron microscopyoptical tweezersmolecular biology techniquesproteomics analysisaxon injury modelsimmunostaininglive imagingquantitative data analysis
Output against the department
Publications526top 5% of dept.15th of 286
this lab
most publishedleast published
Citations80ktop 1% of dept.3rd of 286
this lab
most citedleast cited
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