Stanford University · GeneticsBrunet Aging Lab
Anne Brunet · Stanford, California
Research Focus
Professor Anne Brunet's lab at Stanford focuses on understanding the biological processes of aging and how the brain affects the aging of other organs. They use unique models like the African killifish to study aging due to its short lifespan and develop advanced tools like machine learning and spatial transcriptomics to analyze complex data. By investigating how the peripheral nervous system and immune cells influence the aging process, the lab aims to uncover potential therapies to enhance longevity and counter age-related diseases.
agingperipheral nervous systembrain functionneurodegenerative diseasesimmune cellskillifishlongevitymachine learningneurogenesismulti-omics
Research Aims
5AIM 01Investigate how the brain regulates the aging process of the entire organism.
AIM 02Determine the influence of peripheral nervous system changes on organ aging.
AIM 03Uncover the role of immune cells in brain function during aging.
AIM 04Identify behaviors that predict aging and lifespan in vertebrates.
AIM 05Examine how environmental factors impact the activity of peripheral neurons during aging.
Skills the Lab Values
spatial transcriptomicsmachine learningbehavioral analysiscell culturegenetic screeningCRISPR/Cas technologydata analysisvideo trackingartificial intelligencein vivo imaging
Output against the department
Publications250top 33% of dept.86th of 259
this lab
most publishedleast published
Citations51ktop 12% of dept.31st of 259
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.