University of South Alabama · PharmacologyRich Signaling Lab
Thomas C Rich · Mobile, Alabama
Research Focus
Dr. Thomas C. Rich's lab at the University of South Alabama focuses on understanding how cells communicate internally to regulate their functions. Specifically, the lab studies airway smooth muscle cells and how different receptors within these cells manage signals that are crucial for controlling muscle contraction and relaxation. This research is vital for developing new treatments for asthma, a common respiratory condition affecting many people.
G protein-coupled receptorsairway smooth muscleasthmasignaling pathwayscAMP signaling
Research Aims
3AIM 01Investigate the spatial and temporal dynamics of cAMP/PKA signaling in airway smooth muscle cells.
AIM 02Characterize the unique phosphoproteome signatures generated by different GPCRs.
AIM 03Establish how compartmentalized signaling affects airway smooth muscle function.
Skills the Lab Values
imaging techniquesbiosensor developmentcell cultureprotein analysisphosphoproteomics
Output against the department
Publications159bottom 44% of dept.257th of 462
this lab
most publishedleast published
Citations2.6kbottom 18% of dept.377th of 462
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.