UCUniversity of Cincinnati-Main Campus · Pharmacology
Cardiac Glucose Initiative
Konstantinos Drosatos · Cincinnati, Ohio
Research Focus
Dr. Konstantinos Drosatos' lab at the University of Cincinnati focuses on understanding how diabetes affects heart function, particularly through a protein called GLUT1 that helps transport glucose into heart cells. The lab aims to uncover the mechanisms that lead to heart failure in diabetic patients and explore potential therapies to prevent this condition. Their research could lead to new treatments that improve heart health for individuals suffering from diabetes.
diabetic cardiomyopathyGLUT1heart failureFOXO1KLF5
Research Aims
3AIM 01Delineate the signaling events via which GLUT1 leads to DbCM.
AIM 02Elucidate the cardiotoxic metabolic pathways in DbCM that are controlled by GLUT1.
AIM 03Explore the therapeutic potential and underlying mechanisms of GLUT1 inhibition for DbCM in T2D.
Skills the Lab Values
cell culturemouse modelsmolecular cloningWestern blotmetabolic assays
Output against the department
Publications118bottom 33% of dept.307th of 462
this lab
most publishedleast published
Citations5.3kbottom 39% of dept.281st of 462
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.