Baylor College of Medicine · BiochemistryCancer Immunotherapy Research Lab
Jin Wang · Houston, Texas
Research Focus
Dr. Jin Wang's lab focuses on developing new cancer treatments by targeting specific proteins in cells. The team studies how these proteins influence immune responses in cancer therapy, particularly in the context of experimental treatments that could make current therapies more effective. By investigating the role of RIPK1 — a protein that affects cell survival and immune signaling — they aim to create new drugs that help patients who do not respond to existing cancer immunotherapies.
cancer immunotherapyRIPK1PROTAC technologydrug developmenttumor microenvironment
Research Aims
5AIM 01Develop first-in-class RIPK1 degraders for cancer treatment.
AIM 02Investigate the impact of RIPK1 degradation on tumor immunity.
AIM 03Test the therapeutic efficacy of RIPK1 degraders in preclinical models.
AIM 04Identify biomarkers for predicting patient response to immunotherapy.
AIM 05Enhance cancer immunotherapies by targeting RIPK1.
Skills the Lab Values
medicinal chemistrycell culturemouse modelsproteomicsmolecular biology techniques
Output against the department
Publications640top 6% of dept.23rd of 402
this lab
most publishedleast published
Citations58ktop 4% of dept.15th of 402
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.