University of California-Los Angeles · PhysiologyCannon Lab
Stephen C. Cannon · Los Angeles, California
Research Focus
Professor Stephen C. Cannon's research lab at UCLA focuses on understanding a rare condition called hypokalemic periodic paralysis (HypoPP), which leads to sudden muscle weakness. The lab investigates how specific genetic mutations affect muscle function and explores new treatment options, including pharmacological interventions and gene editing techniques. Their work aims to improve the quality of life for individuals affected by this condition and to find more effective ways to manage and potentially prevent muscle weakness associated with it.
Hypokalemic periodic paralysiscalcium channelssodium channelsgene editingpharmacological treatments
Research Aims
5AIM 01Investigate the molecular mechanisms underlying hypokalemic periodic paralysis
AIM 02Develop new pharmacological therapies to manage acute muscle weakness
AIM 03Explore gene editing techniques to correct genetic mutations responsible for HypoPP
AIM 04Test the efficacy of novel treatments in knock-in mouse models
AIM 05Assess the potential of new approaches to prevent late-onset muscle weakness.
Skills the Lab Values
CRISPR/Cas9gene editingmouse modelspharmacologybiophysical assaysmolecular biologymuscle physiologycomputer modelingdata analysis
Output against the department
Publications174top 40% of dept.114th of 286
this lab
most publishedleast published
Citations10ktop 32% of dept.92nd of 286
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.