University of Alabama at Birmingham · PsychologyYounger Lab
Jarred W. Younger · Birmingham, Alabama
Research Focus
Dr. Jarred W. Younger's lab at the University of Alabama at Birmingham is focused on exploring treatments for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), a debilitating condition affecting many individuals. The lab is currently conducting a clinical trial on low-dose naltrexone (LDN), which is thought to reduce inflammation in the brain and improve symptoms associated with ME/CFS. Through a remote trial design, they aim to make participation accessible to individuals with severe symptoms and gather important data for future studies.
Myalgic EncephalomyelitisChronic Fatigue SyndromeLow-dose naltrexoneNeuroinflammationClinical trialsBrain inflammationFatigue treatmentPain sensitivityCognitive issues
Research Aims
5AIM 01Test the effectiveness of low-dose naltrexone (LDN) in treating ME/CFS
AIM 02Evaluate safety and side effects of LDN
AIM 03Identify biomarkers for LDN response
AIM 04Determine the best dosage for future trials
AIM 05Assess the long-term efficacy of LDN in managing ME/CFS symptoms.
Skills the Lab Values
Clinical trial designRemote study methodologiesNeuroimaging techniquesBlood sample analysisStatistical analysis software (e.g., R, SPSS)Patient enrollment and managementInformed consent processesData collection and reportingBasic laboratory techniques in neuroscience
Output against the department
Publications107bottom 29% of dept.209th of 296
this lab
most publishedleast published
Citations5.0kbottom 43% of dept.169th of 296
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.