University of Kansas · Biomedical EngineeringCancer Metastasis and MK2 Unit
Gregory N Gan · Lawrence, Kansas
Research Focus
Dr. Gregory Gan's lab focuses on understanding how a specific protein, MK2, affects the behavior of head and neck cancer cells, particularly their ability to migrate and invade other tissues. By exploring the role of MK2 in cancer metastasis, the lab aims to develop new strategies that could improve treatments and ultimately enhance survival rates for patients with head and neck squamous cell carcinoma. Their work includes using innovative techniques to study cancer cells and their interactions in a lab setting, which could lead to promising clinical applications.
head and neck cancercancer metastasisMK2tumor microenvironmentradio-sensitivity
Research Aims
3AIM 01Investigate how MK2 regulates tumor cell migration and invasion through specific protein interactions.
AIM 02Examine the effects of MK2 inhibition on the effectiveness of radiotherapy in controlling tumor growth and metastases.
AIM 03Utilize a microphysiological system to recreate tumor environments and test MK2 inhibitors on patient-derived cells.
Skills the Lab Values
cell cultureanimal modelsflow cytometrymolecular biology techniquesin vitro assays
Output against the department
Publications157bottom 34% of dept.389th of 595
this lab
most publishedleast published
Citations3.5kbottom 28% of dept.431st of 595
this lab
most citedleast cited
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