University of Delaware · EngineeringWound Healing and Biomaterials Group
Millicent O Sullivan · Newark, Delaware
Research Focus
Dr. Millicent O'Sullivan's lab at the University of Delaware focuses on innovative strategies to enhance healing in diabetic foot ulcers. The research combines collagen-mimetic peptides with gene-modified collagens to improve the delivery of growth factors directly to chronic wounds. By understanding how to optimize these therapeutic biomaterials, the lab aims to significantly reduce the incidence of amputations and improve overall patient outcomes.
diabetic foot ulcerscollagengene deliverywound healingbiomaterialsimmunomodulatory cytokinesfibroblastsmacrophagestherapeutic peptides
Research Aims
3AIM 01Develop collagen-mimetic peptides that enhance gene delivery in diabetic foot ulcers.
AIM 02Investigate the role of MMPs in controlling growth factor delivery from COATs.
AIM 03Assess how sequential delivery of immunomodulatory cytokines affects wound healing.
Skills the Lab Values
collagen modificationgene transfer techniquescell cultureanimal modelsgrowth factor analysisbiomaterials developmentmolecular biology techniquesPCRimmunological assays
Output against the department
Publications88bottom 19% of dept.226th of 278
this lab
most publishedleast published
Citations2.7kbottom 20% of dept.223rd of 278
this lab
most citedleast cited
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