Tufts University · EngineeringEpilepsy and Cancer Mechanisms Lab
Madeleine Julie Oudin · Medford, Massachusetts
Research Focus
Dr. Madeleine Oudin's research lab focuses on two main areas: tackling pediatric epilepsy through innovative therapies and exploring the role of nerves in cancer metastasis. The lab investigates how specific genetic mutations affect sodium channels in the brain and how the neuronal identity of tumors influences their growth and spread. By understanding these biological mechanisms, the lab aims to develop new, effective treatments for epilepsy and cancer.
pediatric epilepsysodium channelsalternative splicingcancer metastasisneuronal identityanti-epileptic therapymouse modelsneoneurogenesistumor microenvironment
Research Aims
5AIM 01Investigate the role of sodium channel splicing in epilepsy
AIM 02Develop antisent oligonucleotide therapies for pediatric epilepsy
AIM 03Study how neuronal mimicry in tumors affects cancer progression
AIM 04Assess the impact of nerves on tumor microenvironment
AIM 05Explore new non-invasive techniques for monitoring cancer metastasis
Skills the Lab Values
PCRcell cultureanimal modelselectrophysiologyRNA splicing analysisWestern blotimmunohistochemistryfl fluorescent microscopybioinformatics
Output against the department
Publications150bottom 37% of dept.174th of 278
this lab
most publishedleast published
Citations2.2kbottom 17% of dept.232nd of 278
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.