University of Minnesota-Twin Cities · BiochemistryAging and Immune Response Lab
Christina Camell · Minneapolis, Minnesota
Research Focus
Dr. Christina Camell's lab at the University of Minnesota studies how aging affects the immune response to infections like sepsis, particularly focusing on adipose tissue, which is a type of fat tissue. They explore how inflammatory changes in this tissue contribute to older individuals being more susceptible to severe infections. Through their research, they aim to identify new ways to improve treatment and outcomes for elderly patients suffering from sepsis.
sepsisinflammagingadipose tissueimmune responseage-related inflammation
Research Aims
3AIM 01Define the lipolytic response of adipocytes from old vs. young mice.
AIM 02Determine if inflammasome activation and GDF3 mediate reduced lipolysis and increased inflammation in visceral adipose tissue of old mice during LPS challenge.
AIM 03Determine the role of adenosine signaling on lipolysis in old visceral adipose tissue during LPS challenge.
Skills the Lab Values
mouse modelslipolysis measurementimmunohistochemistryflow cytometrycell cultureRNA extractionWestern blotPCRdata analysis
Output against the department
Publications56bottom 10% of dept.363rd of 402
this lab
most publishedleast published
Citations1.9kbottom 7% of dept.373rd of 402
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.