University of Texas Southwestern Medical Center · NeuroscienceTerman Connectivity Lab
Jonathan R Terman · Dallas, Texas
Research Focus
Dr. Jonathan Terman's research lab at UT Southwestern Medical Center focuses on understanding how neurons connect with each other during development and how these connections are maintained into adulthood. Their work primarily investigates the molecular mechanisms of axon guidance using the fruit fly as a model organism. By studying these processes, the lab aims to uncover insights that could lead to new treatments for mental illnesses and other brain disorders caused by disrupted neural connections.
axon guidanceneural connectivityDrosophilasemaphorinsneuronal metabolism
Research Aims
5AIM 01Define the molecular mechanisms of axon navigation.
AIM 02Characterize the intracellular signaling pathways linking guidance cues to axon behavior.
AIM 03Investigate the role of semaphorins and their receptors in neuronal connectivity.
AIM 04Explore how metabolic factors influence neuronal connections.
AIM 05Utilize the Drosophila model to study neural development.
Skills the Lab Values
molecular genetic techniquesbiochemical assayscellular imaginggene editingmotor neuron identification
Output against the department
Publications62bottom 15% of dept.569th of 671
this lab
most publishedleast published
Citations3.7kbottom 27% of dept.488th of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.