UTMThe University of Texas MD Anderson Cancer Center · Biomedical Engineering
Li Lab
Chun Li · Houston, Texas
Research Focus
Dr. Chun Li's lab focuses on developing new therapies for hepatocellular carcinoma (HCC), a type of liver cancer that is becoming increasingly common. The lab is exploring the use of polymeric micelles that can deliver dual drug therapies effectively to target cancer stem cells and other tumor cells. This innovative approach aims to improve treatment outcomes and ultimately provide better survival rates for HCC patients.
Hepatocellular carcinomacancer stem cellspolymeric micellesdual drug therapydrug resistancechemotherapyepithelial-to-mesenchymal transition
Research Aims
3AIM 01Develop a polymeric micelle-based delivery system for HCC therapy.
AIM 02Determine the antitumor efficacy and safety profile of the M-CPA/PTX in preclinical models.
AIM 03Evaluate the mechanisms of action for the M-CPA/PTX treatment in HCC.
Skills the Lab Values
polymeric micelle formulationanimal modelsbiodistribution studiespharmacokinetics analysischemotherapy drug efficacy testingcell culture techniquesapoptosis assaysmass spectrometryliquid chromatography
Output against the department
Publications772top 7% of dept.41st of 595
this lab
most publishedleast published
Citations44ktop 4% of dept.26th of 595
this lab
most citedleast cited
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