New York University · ChemistrySchlick Lab
Tamar Schlick · New York, New York
Research Focus
Dr. Tamar Schlick's research lab at New York University focuses on using advanced computer modeling to understand how the structure of DNA and RNA impacts their function, especially in relation to cancer and viral infections like COVID-19. The lab combines insights from mathematics, engineering, and biology to develop models that explain complex biological processes, such as how chromatin (the material that makes up chromosomes) organizes in the cell and how viruses manipulate their RNA to survive. This work aims to lead to improved diagnostic and therapeutic strategies for various diseases.
RNA ModelingGenome OrganizationViral InfectionsChromatin StructureCancer GenomicsMolecular DynamicsBiophysicsComputational BiologyRNA FrameshiftingBiophysical Modeling
Research Aims
5AIM 01Develop multiscale models to understand chromatin structure in cancer cells.
AIM 02Investigate RNA conformational dynamics in viruses like SARS-CoV-2.
AIM 03Link chromatin structural changes to gene expression modulation.
AIM 04Create a virus topology atlas to explore RNA motifs.
AIM 05Facilitate the design of targeted therapies using insights from biophysical modeling.
Skills the Lab Values
Molecular Dynamics SimulationsComputational ModelingGraph Theory in BiologyRNA Structure AnalysisChromatin ModelingBiophysical Analysis TechniquesPython ProgrammingData VisualizationCollaboration with ExperimentalistsRNA Editing Techniques
Output against the department
Publications459top 22% of dept.47th of 216
this lab
most publishedleast published
Citations16ktop 31% of dept.67th of 216
this lab
most citedleast cited
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