Stony Brook University · BiochemistryMembrane Dynamics Lab
Erwin London · Stony Brook, New York
Research Focus
Erwin London's lab explores the intricate structure and function of cell membranes, focusing on how the composition of lipids affects cellular processes and responses. Using innovative techniques, the team investigates how the organization of membrane lipids influences the behavior of membrane proteins, particularly receptors that play crucial roles in cellular signaling. The lab's research has implications for understanding disease mechanisms and improving vaccine design.
lipid exchangemembrane organizationsphingolipidsinsulin receptorvirus lipid compositionsignal transductionmembrane asymmetryvaccine developmentcell membrane
Research Aims
5AIM 01Investigate how lipid composition affects membrane protein function.
AIM 02Examine the role of lipid asymmetry in membrane signaling.
AIM 03Develop methods to control lipid composition in mammalian cells.
AIM 04Utilize lipid exchange to study viral envelope interactions.
AIM 05Assess how membrane lipids can enhance or inhibit receptor activity.
Skills the Lab Values
lipid exchange techniquescell culturefluorescence microscopybiological assaysmembrane protein studymolecular cloningspectroscopydata modelinglipid composition analysis
Output against the department
Publications270top 25% of dept.101st of 402
this lab
most publishedleast published
Citations23ktop 17% of dept.68th of 402
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.