University of Pennsylvania · Biomedical EngineeringThe MRI Harmony Lab
Sudipto Dolui · Philadelphia, Pennsylvania
Research Focus
The research lab led by Sudipto Dolui at the University of Pennsylvania focuses on improving the quality and reliability of magnetic resonance imaging (MRI) techniques, particularly for studying Alzheimer's disease and related dementias. They aim to develop automated methods for assessing the quality of cerebral blood flow images and harmonizing data collected from different MRI machines. By addressing variability in images from various sources, their work seeks to enhance research accuracy and lead to better diagnostics in aging-related conditions.
Alzheimer's DiseaseCerebral Blood FlowArterial Spin LabelingMRIDeep LearningData HarmonizationQuality ControlClinical ResearchNeuroimagingDementia
Research Aims
5AIM 01Develop automated indices to evaluate quality of cerebral blood flow MRI maps.
AIM 02Harmonize multisite ASL data to reduce variability across scan sites.
AIM 03Implement a deep learning algorithm to identify sources of artifacts in MRI images.
AIM 04Expand harmonization techniques to work across multiple MRI vendor platforms.
AIM 05Demonstrate the effectiveness of these methods in differentiating cognitive impairment in patients.
Skills the Lab Values
Magnetic Resonance Imaging (MRI)Deep LearningData AnalysisQuality Control TechniquesSoftware DevelopmentStatistical AnalysisImage ProcessingResearch MethodologyAutomated Indexing
Output against the department
Publications96bottom 16% of dept.499th of 595
this lab
most publishedleast published
Citations1.3kbottom 9% of dept.543rd of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.