Northwestern University · Biomedical EngineeringAbazeed Lab
Mohamed E. Abazeed · Evanston, Illinois
Research Focus
Dr. Abazeed's lab focuses on understanding the complexities of small cell lung carcinoma (SCLC), a challenging type of cancer that is often resistant to treatment. The lab explores how cancer cells can change their behavior and characteristics in response to therapies, which helps uncover new strategies for overcoming these resistances. By studying the different states of SCLC cells, the team aims to develop innovative therapeutic approaches that can improve treatment outcomes for patients.
small cell lung carcinomacancer heterogeneitycell plasticitychemoresistancetherapeutic strategies
Research Aims
4AIM 01Investigate the extent of genetic and epigenetic diversity in SCLC tumors.
AIM 02Characterize the dynamic phenotypic states of SCLC cells.
AIM 03Understand the role of cellular plasticity in treatment resistance.
AIM 04Develop new therapeutic strategies targeting epigenetic reprogramming.
Skills the Lab Values
single-cell RNA sequencingpatient-derived xenograft modelsfluorescence trackingmathematical modelingbulk genetic analysis
Output against the department
Publications258top 38% of dept.226th of 595
this lab
most publishedleast published
Citations3.2kbottom 25% of dept.448th of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.