AECAlbert Einstein College of Medicine · Biology
Weiss Lab
Louis M. Weiss · Bronx, New York
Research Focus
Dr. Louis M. Weiss's research lab focuses on understanding Toxoplasma gondii, a parasite that causes severe brain infections in individuals with HIV/AIDS. The lab investigates the cyst wall of this parasite, which is crucial for its ability to persist and reactivate in the central nervous system. By identifying proteins that comprise this cyst wall and exploring their roles, the lab aims to develop new strategies for preventing opportunistic infections in immunocompromised patients.
Toxoplasma gondiiAIDSopportunistic infectionscyst wallHIV
Research Aims
5AIM 01Investigate the formation and composition of the T. gondii cyst wall.
AIM 02Identify proteins that may serve as vaccine targets against latent Toxoplasma infections.
AIM 03Develop state-of-the-art methods to characterize T. gondii structures.
AIM 04Explore the role of CST1 in cyst wall assembly.
AIM 05Understand how stress influences T. gondii differentiation.
Skills the Lab Values
proteomicsimmunologic techniquesgenetic techniquestissue culturemass spectrometry
Output against the department
Publications536top 7% of dept.71st of 1,033
this lab
most publishedleast published
Citations26ktop 14% of dept.143rd of 1,033
this lab
most citedleast cited
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