University of Pennsylvania · PharmacologyVoight Islet Lab
Benjamin Franklin Voight · Philadelphia, Pennsylvania
Research Focus
Dr. Benjamin Franklin Voight's lab focuses on understanding how different types of cells in the pancreas work together to regulate blood sugar levels and how their dysfunction can lead to diabetes. They are using advanced techniques to create a detailed map of gene regulation in pancreatic islet cells, with the goal of identifying genetic factors that contribute to diabetes. This work aims to improve patient care and enhance our understanding of diabetes progression.
diabetesgene regulationpancreatic isletssingle-cell analysisbioinformaticsgenetic determinantsdisease progressiongenomicsregulatory circuitryhealthcare improvement
Research Aims
5AIM 01Create the largest map of pancreatic islet cell types
AIM 02Identify genetic determinants linked to diabetes
AIM 03Generate regulatory circuitry for islet cell types
AIM 04Develop robust data integration pipelines
AIM 05Facilitate broad access to diabetes research data through knowledge portals
Skills the Lab Values
single-cell RNA sequencingchromatin accessibility assaysbioinformaticsdata integrationstatistical analysisgenome mappingregulatory element identificationcell culture techniquesmolecular profiling
Output against the department
Publications469top 12% of dept.54th of 462
this lab
most publishedleast published
Citations80ktop 2% of dept.9th of 462
this lab
most citedleast cited
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