Columbia University in the City of New York · PhysiologyDiano Metabolism Lab
Sabrina Diano · New York, New York
Research Focus
Dr. Sabrina Diano's lab studies how certain neurons in the brain control metabolism and eating behavior, focusing on lipid signaling and energy balance. The research looks specifically at how different neuronal populations affect hunger and how their activity changes based on metabolic conditions like fasting or diet-induced obesity. By understanding these mechanisms, the lab aims to uncover new strategies for addressing metabolic disorders.
lipid signalingenergy metabolismappetite regulationmelanocortin signalingmitochondrial dynamicsneurotransmissiondiet-induced obesity
Research Aims
3AIM 01Investigate how Nogo regulates fatty acid metabolism and feeding behavior in AgRP neurons.
AIM 02Differentiate the role of GABAergic and glutamatergic MC4R neurons in feeding and metabolism regulation.
AIM 03Examine the influence of melanocortin signaling in diet-induced obesity.
Skills the Lab Values
cell culturein vivo calcium imaginggenetic manipulationpharmacological assaysmolecular biology techniquesmouse modelsWestern blottingRNA sequencingneuroscience techniquesbehavioral assays
Output against the department
Publications171top 42% of dept.119th of 286
this lab
most publishedleast published
Citations20ktop 13% of dept.36th of 286
this lab
most citedleast cited
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