University of Nebraska Medical Center · BiochemistryOberley-Deegan Radiotherapy Lab
Rebecca E Oberley-Deegan · Omaha, Nebraska
Research Focus
Dr. Rebecca E Oberley-Deegan's lab focuses on enhancing the safety and efficacy of radiation therapy for rectal cancer. The primary research investigates a novel antioxidant drug, BMX-001, which aims to protect normal tissues from damage while targeting cancer cells. The lab conducts preclinical studies and clinical trials to assess BMX-001's protective effects and identify biomarkers for radiation damage.
radiotherapyrectal cancerBMX-001oxidative stressantioxidants
Research Aims
3AIM 01Investigate the mechanisms by which BMX-001 protects normal rectal tissues from radiation-induced damage.
AIM 02Determine the safety and efficacy of BMX-001 in Phase II clinical trials for rectal cancer patients.
AIM 03Identify potential biomarkers for radiation damage and the efficacy of BMX-001 in clinical specimens.
Skills the Lab Values
clinical trial designbiomarker analysisin vivo modelscell cultureoxidative stress assessment
Output against the department
Publications122bottom 33% of dept.268th of 402
this lab
most publishedleast published
Citations2.5kbottom 10% of dept.360th of 402
this lab
most citedleast cited
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