Augusta University · NeuroscienceWang Neurobiology Lab
Qin Wang · Augusta, Georgia
Research Focus
Dr. Qin Wang's lab at Augusta University studies the relationship between brain cell signaling and neurodegenerative diseases, particularly Alzheimer's disease. They focus on how certain genes and signaling pathways that activate brain cells like astrocytes influence disease progression. Additionally, they explore how specific proteins regulate neuron activity, impacting emotional responses and behavior. Their work aims to uncover potential new therapeutic strategies for Alzheimer's and understanding stress-related mental health issues.
Alzheimer's DiseaseastrocytesJAK/STAT signalingCHD7neural circuitsepigenetic regulationstress responsesbehavioral neurosciencecognitive deficits
Research Aims
5AIM 01Investigate the role of the OSMR/JAK/STAT signaling pathway in initiating astrocyte reactivity related to Alzheimer's disease.
AIM 02Examine how AD-related astrocyte reactivity affects neuronal and microglial functions.
AIM 03Test the effectiveness of blocking OSMR signaling on AD-related cognitive deficits.
AIM 04Explore how CHD7 regulates neuronal activity in the anterior cingulate cortex during stress responses.
AIM 05Determine the role of CHD7 in activity-dependent gene transcription in postmitotic neurons.
Skills the Lab Values
cell culturemouse modelsgene expression analysisimmunohistochemistrybehavioral assaysRNA sequencingWestern blotchromatin immunoprecipitation (ChIP)protein assays
Output against the department
Publications841top 5% of dept.34th of 671
this lab
most publishedleast published
Citations18ktop 23% of dept.155th of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.