University of Washington-Seattle Campus · PharmacologyThe Microbiome Metabolism Lab
Libin Xu · Seattle, Washington
Research Focus
Libin Xu's lab at the University of Washington focuses on understanding how exposure to benzalkonium chloride (BAC), a common disinfectant, impacts the gut microbiome and liver metabolism. This research is particularly relevant given the increased use of disinfectants during the COVID-19 pandemic. The lab employs animal models and human samples to investigate how BAC alters microbial diversity and metabolic processes, aiming to shed light on the health implications of these environmental exposures.
Benzalkonium Chloridegut microbiomeliver metabolismenvironmental contaminantsCOVID-19
Research Aims
3AIM 01Characterize the impact of BAC exposure on gut microbiome diversity and function in mice.
AIM 02Measure the effect of BAC exposure on bile acid and lipid metabolism in the liver.
AIM 03Evaluate the relationship between BAC levels and gut microbiome diversity in humans.
Skills the Lab Values
animal modelsmicrobiome analysismetabolomicsgene expression analysisdata analysis with Python
Output against the department
Publications192top 46% of dept.211th of 462
this lab
most publishedleast published
Citations6.9kbottom 49% of dept.237th of 462
this lab
most citedleast cited
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