Stanford University · BiologySkotheim Lab
Jan M Skotheim · Stanford, California
Research Focus
Dr. Jan M. Skotheim's lab at Stanford University focuses on understanding how cells control their growth and division, with a particular emphasis on budding yeast as a model system. The lab aims to uncover the molecular mechanisms that link cell growth to cell division, and how these processes are disrupted in cancer. Their research has significant implications for both basic biology and medical applications, especially in developing new cancer treatments.
cell divisioncell growthcancer biologyG1/S transitioncell cycle regulationeukaryotic cellsmolecular mechanismstranscription factorstherapeutic strategies
Research Aims
5AIM 01Investigate how cell growth triggers division in budding yeast
AIM 02Identify the molecular mechanisms regulating cell size at the G1/S transition
AIM 03Explore new functions of Rb pathway components in cancer
AIM 04Develop innovative strategies targeting the Cyclin D-Cdk4/6-Rb-E2F pathway
AIM 05Uncover novel insights into cellular machinery governing cell division and growth control.
Skills the Lab Values
cell culturemolecular cloningPCRcell cycle analysisprotein purificationWestern blottingRNA extractionmicroscopygenetic analysis
Output against the department
Publications175top 38% of dept.389th of 1,033
this lab
most publishedleast published
Citations11ktop 33% of dept.345th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.