Icahn School of Medicine at Mount Sinai · Microbiology & ImmunologyViral Pathogenesis and Antibody Development Lab
Benhur Lee · New York, New York
Research Focus
Dr. Benhur Lee's lab is focused on researching henipaviruses and pararubulaviruses, which are serious threats to public health due to their high fatality rates and potential for causing pandemics. The lab develops antibodies that can neutralize these viruses and studies how they infect human cells. The goal is to provide effective treatments and preventive strategies against these dangerous viruses, enhancing global health security.
henipavirusespararubulavirusesmonoclonal antibodiesviral pathogenesispublic healthpandemic preparedness
Research Aims
5AIM 01Develop broadly neutralizing antibodies against henipaviruses.
AIM 02Assess the protective efficacy of engineered antibodies in animal models.
AIM 03Investigate the cellular tropism of pararubulaviruses in human cells.
AIM 04Characterize the receptor usage pathways of emerging paramyxoviruses.
AIM 05Establish a pathogenic animal model to study viral infections.
Skills the Lab Values
antibody engineeringmolecular biologyanimal modelsreverse geneticscell cultureviral infection assaysimmunization protocolsexplant modelsepitope mapping
Output against the department
Publications307top 15% of dept.75th of 486
this lab
most publishedleast published
Citations22ktop 17% of dept.85th of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.