UWMUniversity of Wisconsin-Madison · Biology
Center for Female Fertility Research
Joan S Jorgensen · Madison, Wisconsin
Research Focus
Dr. Joan S Jorgensen's lab focuses on understanding key mechanisms that influence female fertility, particularly how specific proteins impact the development of ovarian follicles and the implantation of embryos. Through their research, the lab investigates the critical roles of Iroquois homeobox proteins in these processes, aiming to contribute to better understanding of fertility issues such as premature ovarian reserve loss and implantation failures. Ultimately, this research seeks to uncover strategies that might improve health outcomes related to female reproductive success.
Iroquois homeobox proteinsfemale fertilityoocyte developmentimplantationplacentationembryo developmentovarian reservefollicle formationcell communication
Research Aims
3AIM 01Discover the role of Irx3 in oocyte regulation during ovary development.
AIM 02Investigate how Irx3 influences stromal-endothelium interactions during pregnancy establishment.
AIM 03Examine the signaling and localization of cytoskeletal machinery in relation to Irx3 presence.
Skills the Lab Values
mouse modelshistologygenetic manipulationimmunofluorescencePCRcell cultureRNA sequencingflow cytometrydata analysis
Output against the department
Publications60bottom 15% of dept.873rd of 1,033
this lab
most publishedleast published
Citations1.3kbottom 8% of dept.955th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.