Brown University · BiologyKurtis Lab
Jonathan D. Kurtis · Providence, Rhode Island
Research Focus
Dr. Jonathan D. Kurtis leads a research lab focused on developing new treatments for severe malaria, specifically targeting a protein called PfGARP found on the surface of malaria-infected red blood cells. The lab's work aims to create a novel class of antimalarial drugs that could effectively combat the rising issue of drug resistance in Plasmodium falciparum, the parasite responsible for malaria. Through high-throughput drug screening and testing in humanized mouse models, the lab seeks to discover and refine new drugs to improve health outcomes in affected populations.
antimalarial drugsPfGARPmalariadrug resistancehigh-throughput screening
Research Aims
4AIM 01Develop new antimalarial drugs targeting PfGARP.
AIM 02Conduct high-throughput drug screens to identify effective compounds.
AIM 03Optimize and select candidates for further study.
AIM 04Validate drug candidates in humanized mouse models.
Skills the Lab Values
high-throughput drug screeningantibody productioncell culturehumanized mouse modelsdrug candidate optimization
Output against the department
Publications71bottom 20% of dept.830th of 1,033
this lab
most publishedleast published
Citations2.5kbottom 18% of dept.847th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.