Washington University in St Louis · Biomedical EngineeringAortic Insight Lab
Jessica Wagenseil · Saint Louis, Missouri
Research Focus
Jessica Wagenseil's lab focuses on the study of ascending thoracic aortic aneurysms, which are dangerous cardiovascular conditions. The lab combines animal models, advanced computational techniques, and patient imaging data to identify potential biomarkers that can predict the failure of aneurysms. By examining a mouse model and utilizing complex simulations, the team aims to improve assessment and treatment strategies for patients at risk of aortic dissection or rupture.
ascending thoracic aortic aneurysmbiomarkerscomputer modelingMarfan Syndromemultiscale modeling
Research Aims
3AIM 01Characterize aneurysm progression in a mouse model of Marfan Syndrome using detailed quantitative analysis.
AIM 02Develop a multiscale multiphysics computational model to simulate ATAA growth and remodeling.
AIM 03Generate virtual patient models from human imaging data to predict aneurysm progression and failure.
Skills the Lab Values
animal models developmentcomputer simulationsbiomechanical testingdata analysismachine learning
Output against the department
Publications107bottom 19% of dept.479th of 595
this lab
most publishedleast published
Citations4.8kbottom 37% of dept.376th of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.