The University of Texas Health Science Center at San Antonio · GeneticsHuang Lab
Tim H.-M. Huang · San Antonio, Texas
Research Focus
Dr. Tim H.-M. Huang's lab at the University of Texas Health Science Center focuses on understanding the role of tumor-macrophage hybrid cells in prostate cancer progression, particularly in cases resistant to traditional androgen receptor signaling inhibitors. These hybrid cells may help cancer evade the immune system and spread throughout the body. This research aims to uncover new treatment strategies against advanced prostate cancer by profiling these unique cells and their mechanisms.
prostate cancertumor-macrophage hybrid cellsmetastasiscancer immunologytreatment resistance
Research Aims
3AIM 01Define how tumor-macrophage hybrid cells contribute to prostate cancer metastasis.
AIM 02Explore the immunoevasive features of hybrid cells by studying transcriptional changes.
AIM 03Investigate how mechanical stress affects the viability of tumor-macrophage hybrid cells in circulation.
Skills the Lab Values
cell cultureflow cytometryRNA sequencingimmunophenotypingWestern blotmicrofluidic chip technologyatomic force microscopytranscriptomic analysis
Output against the department
Publications271top 31% of dept.79th of 259
this lab
most publishedleast published
Citations7.4kbottom 41% of dept.153rd of 259
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.