University of Illinois Urbana-Champaign · BiologyLaboratory for Embryonic Development Research
Jing Yang · Champaign, Illinois
Research Focus
Dr. Jing Yang's lab at the University of Illinois is focused on understanding the critical processes that occur during the transition from oocyte to embryo, specifically in vertebrates like frogs and zebrafish. They investigate how the cellular components and maternal RNA are reorganized to support successful reproduction. Their research aims to uncover new mechanisms that could explain unexplained infertility in humans, enhancing reproductive health.
oocyte-to-embryo transitioncytoplasmic remodelingmaternal RNAendoplasmic reticuluminfertilityenvironmental pollutantsreproductive healthXenopusphase transitionCdc42 signaling
Research Aims
5AIM 01Investigate the role of endoplasmic reticulum in RNA sorting during the oocyte-to-embryo transition.
AIM 02Determine how environmental factors, like phthalates, affect cytoplasmic remodeling.
AIM 03Explore the evolutionary conservation of cytoplasmic remodeling mechanisms.
AIM 04Examine the Cdc42-Wasl-Arp2/3 signaling pathway's impact on organelle remodeling during oocyte maturation.
AIM 05Identify novel mechanisms for improving reproductive success in vertebrates.
Skills the Lab Values
RNA extractioncell cultureembryo manipulationmolecular cloningmicroscopyWestern blotphase contrast microscopyoptogeneticsquantitative PCRenvironmental exposure assessments
Output against the department
Publications111bottom 39% of dept.633rd of 1,033
this lab
most publishedleast published
Citations31ktop 10% of dept.108th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.