UTHThe University of Texas Health Science Center at Houston · Neuroscience
The Microbiome Mind Lab
Juneyoung Lee · Houston, Texas
Research Focus
Dr. Juneyoung Lee's lab at the University of Texas Health Science Center focuses on understanding the connection between the gut microbiome and brain health, particularly in disorders like Alzheimer's disease and cerebral amyloid angiopathy (CAA). The lab investigates how B cells, a type of immune cell, can influence neuroinflammation and cognitive decline as we age. Their research aims to uncover new ways to target these cells to improve outcomes for patients suffering from age-related brain diseases.
gut microbiomeneuroinflammationB cellscerebral amyloid angiopathyAlzheimer's disease
Research Aims
4AIM 01Explore the role of B cells in neuroinflammation associated with cerebral amyloid angiopathy.
AIM 02Investigate how gut dysbiosis can lead to B cell-mediated neuroinflammation.
AIM 03Determine the mechanisms by which CAA affects cognitive function through immune response.
AIM 04Assess the impact of the microbiota-gut-brain axis on neurodegenerative diseases.
Skills the Lab Values
flow cytometryfecal microbiota transplantationsingle-cell RNA sequencingspatial gene expression profilingimmunohistochemistry
Output against the department
Publications959top 4% of dept.25th of 671
this lab
most publishedleast published
Citations21ktop 20% of dept.131st of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.