Yale University · GeneticsMuzumdar Lab
Mandar Deepak Muzumdar · New Haven, Connecticut
Research Focus
Dr. Mandar Muzumdar's lab at Yale University focuses on understanding the complex interactions between diet, genetics, and pancreatic cancer development. Their research explores how dietary factors like fatty acids and medications such as incretin mimetics influence cancer risk and progression, particularly in pancreatic ductal adenocarcinoma (PDAC). They employ advanced techniques to determine molecular mechanisms and develop strategies for prevention and treatment.
pancreatic cancerdietary fatsGLP-1 receptor3D genome organizationobesitycancer signalinglipidomicstumorigenesisgenetically engineered mice
Research Aims
3AIM 01Investigate how incretin mimetics affect pancreatic cancer risk in obese and lean contexts.
AIM 02Determine the role of specific dietary fats in promoting pancreatic tumor development.
AIM 03Explore the impact of 3D genome organization on cancer progression in pancreatic and lung tumors.
Skills the Lab Values
mouse modelslipidomic analysisgenetic manipulationcell culturesingle-cell sequencingdimensional genome analysispharmacological studiesimmunohistochemistrycomputational biology
Output against the department
Publications71bottom 17% of dept.214th of 259
this lab
most publishedleast published
Citations6.5kbottom 34% of dept.170th of 259
this lab
most citedleast cited
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