University of Nebraska Medical Center · BiologyThe Tryptophan Nexus
Rey A Carabeo · Omaha, Nebraska
Research Focus
Dr. Rey A Carabeo's lab at the University of Nebraska Medical Center studies the bacterium Chlamydia trachomatis, which causes infections and relies on host cells for nutrients. The lab focuses on understanding how this pathogen regulates its metabolic processes, specifically the tryptophan biosynthesis pathway, to survive in different environments. They investigate gene expression regulation, aiming to uncover new insights into the bacterial adaptation mechanisms in response to nutrient availability.
Chlamydia trachomatistrp operongene regulationmetabolic pathwaysnutritional requirements
Research Aims
5AIM 01Investigate the regulation of the trp operon in Chlamydia trachomatis.
AIM 02Explore the role of the YtgR repressor in gene expression.
AIM 03Examine the metabolic consequences of tryptophan biosynthesis regulation.
AIM 04Analyze serine utilization in relation to metabolic pathways.
AIM 05Study the effects of iron on expression of tryptophan synthesis genes.
Skills the Lab Values
Molecular cloningGene expression analysisTranscription regulation studiesCell culture techniquesProtein purification
Output against the department
Publications62bottom 16% of dept.867th of 1,033
this lab
most publishedleast published
Citations2.4kbottom 17% of dept.860th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.