Stanford University · BiologyThe Alzheimer’s Cell Initiative
Inma Cobos · Stanford, California
Research Focus
Dr. Inma Cobos' research lab at Stanford focuses on understanding how different brain cells respond to Alzheimer's disease. By studying humanized mouse models, the lab aims to identify which types of brain cells are especially vulnerable to the disease and how they interact with each other. Their work will help uncover the mechanisms that lead to cognitive deficits and advance the understanding of Alzheimer's pathology.
Alzheimer's Diseasemultiomicsneurodegenerationcell vulnerabilityGABAergic interneuronstau pathologyhumanized mouse modelssingle-cell RNA-seqbehavioral analysis
Research Aims
3AIM 01Characterize the early changes in vulnerable GABAergic interneurons associated with Alzheimer's pathology.
AIM 02Map cell-type-specific vulnerabilities and interactions related to amyloid and tau proteinopathies using spatial multiomics.
AIM 03Assess the effects of amyloid and tau on the molecular properties of vulnerable brain cell types.
Skills the Lab Values
single-cell RNA sequencingelectrophysiologyFACS (Fluorescence-Activated Cell Sorting)EEG (electroencephalography)machine learningspatial multiomicsdata integrationanimal modelscell culture
Output against the department
Publications74bottom 21% of dept.816th of 1,033
this lab
most publishedleast published
Citations6.4kbottom 46% of dept.559th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.