Icahn School of Medicine at Mount Sinai · GeneticsBacterial Epigenomics and Neuropsychiatry Lab
Gang Fang · New York, New York
Research Focus
The lab of Gang Fang focuses on understanding the roles of bacterial epigenomes and complex gene splicing in neuropsychiatric disorders. They utilize advanced sequencing technologies to explore how bacteria adapt to their environments and how variations in gene splicing affect brain function related to disorders like schizophrenia and autism. Their research aims to identify new biomarkers and therapeutic targets that can improve treatment outcomes for these conditions.
bacterial epigenomicsmicrobiome analysisalternative splicingpsychiatric diseasesDNA methylationlong-read sequencingneurodevelopmental disordersgene regulationstress response
Research Aims
5AIM 01Map bacterial DNA methylation events to understand stress adaptation.
AIM 02Characterize the complex alternative splicing of genes related to psychiatric disorders.
AIM 03Develop better metagenomic tools for analyzing low-abundance bacteria.
AIM 04Explore the interactions between bacterial epigenomes and host environments.
AIM 05Assess how genetic variations influence neuronal maturation and synaptic function.
Skills the Lab Values
long-read sequencingcell culturesingle-cell RNA sequencingbioinformaticsmicrobiome analysisdata visualizationmolecular cloningPCRDNA extraction
Output against the department
Publications356top 23% of dept.59th of 259
this lab
most publishedleast published
Citations9.7kbottom 49% of dept.131st of 259
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.