University of California-Santa Cruz · BiochemistryCell Growth and Size Dynamics Lab
Douglas R. Kellogg · Santa Cruz, California
Research Focus
Dr. Douglas R. Kellogg's lab at UC Santa Cruz focuses on understanding how cells control their growth and size, fundamental processes that are crucial for healthy cell function. They explore the signals and mechanisms that link growth to cell cycle progression, particularly through a network known as TORC2. By studying these processes in yeast, the lab aims to uncover insights that could impact our understanding of cancer growth and offer pathways for new treatments.
cell growthcell sizecell cycleTORC2eukaryotic cellscancer pathologysignal transductionnutrient signalingcell signaling
Research Aims
5AIM 01Investigate how cells measure and limit their growth to control size.
AIM 02Explore the relationship between nutrient availability and cell growth.
AIM 03Identify the signaling networks involved in cell size regulation.
AIM 04Test hypotheses related to proportional growth and cell cycle progression.
AIM 05Map the conserved mechanisms of cell growth control across different organisms.
Skills the Lab Values
cell cultureyeast geneticssignal transduction assaysfluorescence microscopymolecular cloningPCRWestern blottinggrowth assaysdata analysis techniques
Output against the department
Publications90bottom 21% of dept.317th of 402
this lab
most publishedleast published
Citations5.1kbottom 30% of dept.282nd of 402
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.