University of Vermont · PharmacologyCardiovascular Stress Response Lab
Benedek Erdos · Burlington, Vermont
Research Focus
Dr. Benedek Erdos's lab at the University of Vermont focuses on understanding how stress affects blood pressure and heart health. The research investigates a specific signaling pathway in the brain that can lead to heightened sensitivity to stress, which contributes to the development of hypertension. By studying this mechanism, the lab aims to find new ways to treat high blood pressure that is aggravated by psychological stressors.
HypertensionCardiovascular DiseaseStress ResponseBDNFmTORNeuroscienceBrain FunctionNeuroendocrine RegulationPsychological Stress
Research Aims
3AIM 01Investigate how mTORC1 activation in the hypothalamus affects blood pressure and cardiovascular stress responses.
AIM 02Determine the effects of BDNF-mTORC1 signaling on neuronal characteristics related to high blood pressure.
AIM 03Test if blocking BDNF-mTORC1 signaling can prevent hypertension caused by chronic stress.
Skills the Lab Values
In vivo experimental techniquesPatch-clamp electrophysiologyViral vector-mediated gene manipulationTelemetry for physiological monitoringImmunofluorescenceNeuronal morphology analysisData analysis with statistical softwareAnimal handling and careMicroscopy techniques
Output against the department
Publications86bottom 20% of dept.369th of 462
this lab
most publishedleast published
Citations1.3kbottom 6% of dept.434th of 462
this lab
most citedleast cited
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